The giant-sized, square bound Amazing Spider-Man #102 features the origin story and second appearance of Morbius (Marvel spelled Morbius incorrectly on the cover - check it out!).   Lizard also makes an appearance.  It has the first (highly-collectible) picture frame cover in the ASM run, drawn by Gil Kane, who also did the interior art.  Story is by Roy Thomas.  This book is graded 9.4 NM with off-white to white pages by CGC.  Its alignment is pretty nice and the colors are vivid.